Players may also interact with debris and other items with their empty hands. To accomplish these tasks, players carry with them a mop, to help clean up any blood pools or soot found around the station, a sensor device, to detect traces of biological or non-biological messes, and a small PDA to take notes on the level. These include stacking items like crates and barrels in a designated stacking area, and filing disaster reports on the events and deaths that took place in a corresponding level. Tasks include gathering and disposing of debris, including, dismembered bodies of aliens and humans, spent shell casings and broken glass, restocking of wall-mounted first aid kits, repairing bullet holes in walls, and cleaning of blood splatter and soot marks from floors, walls and ceilings, as well as secondary bonus tasks.

In Viscera Cleanup Detail, players are given the role of 'Space-Station Janitors', tasked with cleaning and repairing facilities that have been the scene of bloody battles during an alien invasion or other form of disaster.

The full release became available on 23 October 2015. The game was developed and published by South Africa-based indie developer studio RuneStorm and was released on 4 April 2014 through Steam Early Access. Viscera Cleanup Detail is a science fiction simulation video game where players are tasked to clean up the bloody aftermath of a successfully repulsed alien invasion.

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